If you are a Mayo Clinic patient, this could Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. Epub 2006 Mar 22. It works by . 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (in Cafergot, in Migergot), methylergonovine (Methergine), methysergide (Sansert; no longer available in the U.S.), and pergolide (Permax; no longer available in the U.S.); medications for high blood pressure, heart failure, or an irregular heartbeat. amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. The extended-release tablet usually is taken once daily in the morning. People with kidney problems should be able to take the usual dose of isosorbide mononitrate (Monoket). It can make you really dizzy. The tablet usually is taken two or three times daily. Consult your doctor before breast-feeding. Along with its needed effects, a medicine may cause some unwanted effects. Isosorbide mononitrate Aspirin Prescription only Prescribed for Angina Pectoris Prophylaxis, Heart Failure. This medication belongs to a class of drugs known as. Copyright, 2023. This does not necessarily mean no interactions exist. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Duplication for commercial use must be authorized by ASHP. It is used to treat and prevent a wide range of different conditions. Licorice. To provide you with the most relevant and helpful information, and understand which flushing - try to cut down on coffee, tea and alcohol because they can make flushing worse. Unless there is a specific reason you need the brand, the generic medication will be a better value. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Other side effects not listed may also occur in some patients. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. https://naturalmedicines.therapeuticresearch.com. Accessed Sept. 7, 2022. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Do not stop taking it without consulting your doctor. This is called a medicine interaction. All rights reserved. Isosorbide Mononitrate (Oral Route) - Mayo Clinic Cleophas TJ, Niemeyer MG, van Der Wall EE. Cao HY, Wu HD, Song ZK, Tang ML, Yang S, Liu Y, Qin L. Pan Afr Med J. In: Textbook of Natural Medicine. The effects of this exposure on a nursing infant are unknown. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. Isosorbide mononitrate dose and side-effects info | Patient https://naturalmedicines.therapeuticresearch.com. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). The most common side-effect is headache. Don't drink alcohol while taking isosorbide mononitrate (Monoket). If you have ever had an allergic reaction to a medicine. MeSH If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Do not take more or less of it or take it more often than prescribed by your doctor. Isosorbide mononitrate belongs to the group of medicines called nitrates. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. This should pass after a few days. It is also important information to carry with you in case of emergencies. Natural Medicines. If you are having difficulty accessing this website, please call or email us at (855) 268-2822 or ada@goodrx.com so that we can provide you with the services you require through alternative means. For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). Herbal supplements are natural, so they must be safe, right? Your doctor may tell you to take a pain reliever to treat your headaches. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. The herb licorice may lower warfarin levels and can add to digoxin's effects. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. Nitrates (eg, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin). Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. Saper RB. Clipboard, Search History, and several other advanced features are temporarily unavailable. For details see our conditions. Take your next dose at the regular time. (2) One in 3 patients never experienced headache from the given dosages. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Herbal medications in cardiovascular medicine. https://naturalmedicines.therapeuticresearch.com. Some people feel dizzy or fall when changing positions, such as going from sitting to standing. It does not have such side effects. If you become pregnant while taking isosorbide, call your doctor. Enter other medications to view a detailed report. Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. Highly clinically significant. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Registered number: 10004395 Registered office: Fulford Grange, Micklefield Lane, Rawdon, Leeds, LS19 6BA. Bethesda, MD 20894, Web Policies It is unknown if this medication passes into breast milk. St. John's wort. You can consult me online for homeopathic treatment. Isosorbide mononitrate (Monoket) works slowly to help prevent chest pain. It's usually not a problem for most people unless you drink alcohol or take other medications that can also lower your blood pressure. Take care, thanks. Thirty percent of the patients never experienced headache from the given dosages. Many people using this medication do not have serious side effects. Dehydration in Buspar, how severe and when it was recovered? Accessed Sept. 7, 2022. Tachjian A, et al. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). tell your doctor if you are taking or have recently taken riociguat (Adempas) or a phosphodiesterase inhibitor (PDE-5) such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), and vardenafil (Levitra, Staxyn). Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. The Swedish Multicentre Group. Continue to take isosorbide even if you feel well. Copyright 2023 IBM Watson Health. Isosorbide dinitrate (Isordil) is available as both a short-acting tablet and long-acting capsule. These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. Hawthorn. This content does not have an English version. Isosorbide mononitrate (Monoket) is a nitrate vasodilator. Take this medication by mouth as directed by your doctor, usually twice a day. Accessed Sept. 7, 2022. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Tolerance is more likely to happen if you don't take your dose at the same time every day. St. Joseph 81 mg Aspirin Enteric Safety-Coated. Medicines containing Isosorbide Mononitrate. View more. Isosorbide (C6H10O4), also called D-Isosorbide dinitrate, is a bio-product sourced from starch. Isosorbide mononitrate is very similar to isosorbide dinitrate. Talk to your provider if you continue to feel dizzy or have a fast heart rate a week after starting isosorbide mononitrate (Monoket). As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. It might help to take isosorbide mononitrate and dinitrate after meals. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. It is important that you follow the instructions your doctor gives to you about when to take your doses. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Along with its needed effects, a medicine may cause some unwanted effects. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API). Bauer B (expert opinion). Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Isosorbide mononitrate helps to prevent angina chest pain from developing. Browse all drugs on eHealthMe. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. Do not take a double dose to make up for a missed one. If you have any questions about this medicine ask your pharmacist. Usually avoid combinations; use it only under special circumstances. https://naturalmedicines.therapeuticresearch.com. 1998 Oct;61(10):577-83. other information we have about you. 55 ratings on Drugs.com. Many common herbal supplements interact with common heart medicines. . Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. Do infrared saunas have any health benefits? You will find a full list in the manufacturer's information leaflet supplied with your medicine. The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. Contact your provider right away if you feel as if you are going to pass out and are experiencing an irregular heartbeat, nausea, vomiting, changes in vision, more sweating, or cold and clammy skin. Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. If you have an eye condition called glaucoma. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. Theyre fast, easy-to-use and free! Unauthorized use of these marks is strictly prohibited. We asked 34 people what they think about isosorbide mononitrate (Monoket): Get Isosorbide mononitrate (Monoket) for as low as $29.86, 180 tablets of isosorbide mononitrate 10mg. 5.0 out of 10 from a total of Isosorbide dinitrate dose 30-120 mg daily in divided doses. The extended-release tablet usually is taken once daily in the morning. What conditions does Isosorbide Mononitrate treat? An official website of the United States government. Isosorbide mononitrate has an average rating of View interaction reports for isosorbide mononitrate and the medicines listed below. Alcohol can make the side effects from isosorbide worse. Coenzyme Q-10 Natural Medicines. Real test is coronary angiography. Patient is a UK registered trade mark. MBBS, MS - General Surgery, mch neuro surgery. Trapidil is as effective as isosorbide-dinitrate for treating stable angina pectoris: a multinational, multicenter, double-blind, randomized study. This medicine is available only with your doctor's . 7 disease interactions. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks (chest pain). Therefore, oral nitrates should not be used by patients who are sensitive to the effects of hypotension, such as those with pre-existing hypotension, shock, vascular collapse or significant cerebrovascular disease, significant anaemia or hypothyroidism. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. AHFS Patient Medication Information. Isosorbide mononitrate helps to prevent angina chest pain from developing. Take isosorbide exactly as directed. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Your doctor will probably tell you not to take isosorbide if you are taking one of these medications. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. A total of 195 drugs are known to interact with isosorbide mononitrate: A total of 330 drugs are known to interact with aspirin: A total of 239 drugs are known to interact with nitroglycerin: No known alcohol/food interactions. All rights reserved. Watch for any symptoms that you may be having a drug interaction, such as: Mayo Clinic does not endorse companies or products. Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. You may report side effects to Health Canada at 1-866-234-2345. 41% of reviewers reported a positive effect, while 50% reported a negative effect. This is called tolerance, and it cannot be fixed by raising the dose of the medication. Select a condition to view a list of medication options. In Canada - Call your doctor for medical advice about side effects. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat. You may report side effects to the FDA at 1-800-FDA-1088. Isosorbide is in a class of medications called vasodilators. . 2005 - 2023 WebMD LLC. About one-half of adults in the United States say they have used one or more supplements in the past 30 days. Consult your doctor for more details. https://naturalmedicines.therapeuticresearch.com. Accessed Sept. 7, 2022. We study millions of patients and 5,000 more each day. Do not stop taking isosorbide without talking to your doctor. Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. isosorbide mononitrate (Rx) Brand and Other Names: Imdur, Monoket, more. Do not start, stop, or change the dosage of any medicines without your doctor's approval. This information is aggregated and used to produce personalized reports that patients can reference. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. List of Antianginal agents (antianginal drugs) - Drugs.com The narrowing makes it more difficult for blood to flow to your heart muscle. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Do not double the dose to catch up. Some of these interactions can be life-threatening. Please enable it to take advantage of the complete set of features! Dated August 2017. I took this for 4 days, and my headaches were unbearable. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. WebMD does not provide medical advice, diagnosis or treatment. If we combine this information with your protected Keep all medications away from children and pets. Isosorbide mononitrate is used to prevent chest pain ( angina) in patients with a certain heart condition ( coronary artery disease ). Information is also available online at https://www.poisonhelp.org/help. Isosorbide mononitrate - UpToDate It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Isosorbide mononitrate (Monoket) is not known to affect the kidneys. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. 72% of reviewers reported a positive effect, while 12% reported a negative effect. 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. Garlic. Take the missed dose as soon as you remember it. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. It works to relax your blood vessels. It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Generic alternatives may be available. So get a ct scan brain apart from cardiology workup. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Isosorbide mononitrate - Wikipedia It has a very short duration of action and may not be suitable for some people. Isosorbide mononitrate: effectiveness, side effects, alternatives information is beneficial, we may combine your email and website usage information with Then, there was a two-week placebo washout, after which the alternative treatment was given. This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way. 7.6 out of 10 from a total of Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Let your provider know if they are excessive. This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). Click here for an email preview. the unsubscribe link in the e-mail. Your doctor will prescribe you a short-acting nitrate for you to take if this happens. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. Try to keep your regular appointments with your doctor. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location one that is up and away and out of their sight and reach. But only about 25% of people who take herbal supplements tell their health care providers. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. Follow directions about how much medicine to take. Get emergency help immediately if any of the following symptoms of overdose occur: bulging soft spot on the head of an infant, change in the ability to see colors, especially blue or yellow, feeling of constant movement of self or surroundings. It is best not to drink alcohol while you are on isosorbide mononitrate. Imdur vs. Isordil - RxList Headache is often a sign that this medication is working. Change positions slowly until your body is used to the medication. It can cause your blood pressure to become dangerously low. Yes, it's good for health but don't take it excesse in amount, use once daily for 1 month then stop it or take once a weekly. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. Herbal supplements and heart medicines may not mix - Mayo Clinic Isosorbide mononitrate. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Use of herbal products and potential interactions in patients with cardiovascular diseases. Accessed Sept. 7, 2022. This product is available in the following dosage forms: There is a problem with Am J Ther. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. All rights reserved. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Last Revised - 09/15/2019. To help you remember, take it at the same times each day. Always consult your healthcare provider. Mayo Clinic. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. Isosorbide is a medication used to treat and prevent angina pectoris in patients with coronary heart disease. [2] This medication belongs to a class of drugs known as nitrates. Talk to your pharmacist for more details. Eur Heart J. In case of overdose, call the poison control helpline at 1-800-222-1222. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. B12 and folic acid is essential along with iron. Portions of this document last updated: Feb. 01, 2023. Breastfeeding:There is data that nitrates are excreted in breast milk and may cause methemoglobinemia in infants.