Florida 10th Congressional District Candidates 2022, Articles C

Ritonavir-Boosted Nirmatrelvir (Paxlovid), Table: Characteristics of Antiviral Agents, Including Antibody Products, Table: Characteristics of Immunomodulators, Table: Characteristics of Miscellaneous Drugs, Therapeutic Management of Nonhospitalized Children With COVID-19, Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications, Liverpool COVID-19 Drug Interactions website, University of Waterloo/University of Toronto drug interaction guide, Therapeutic Management of Nonhospitalized Adults With COVID-19, Therapeutic Management of Hospitalized Children With COVID-19, https://www.ncbi.nlm.nih.gov/pubmed/26878082, https://www.ncbi.nlm.nih.gov/pubmed/34726479, https://www.fda.gov/media/155050/download, https://www.ncbi.nlm.nih.gov/pubmed/35172054, https://www.ncbi.nlm.nih.gov/pubmed/34937145, https://www.ncbi.nlm.nih.gov/pubmed/34914868, https://www.pfizer.com/news/press-release/press-release-detail/pfizer-reports-additional-data-paxlovidtm-supporting, https://www.ncbi.nlm.nih.gov/pubmed/35734084, https://www.ncbi.nlm.nih.gov/pubmed/36001529, https://www.ncbi.nlm.nih.gov/pubmed/35986628, https://www.ncbi.nlm.nih.gov/pubmed/35263535, https://www.ncbi.nlm.nih.gov/pubmed/35085683, https://www.ncbi.nlm.nih.gov/pubmed/35461811, https://www.biorxiv.org/content/10.1101/2022.01.17.476644v1, https://www.fda.gov/media/155194/download, https://www.ncbi.nlm.nih.gov/pubmed/36069968, https://www.ncbi.nlm.nih.gov/pubmed/35737946, https://www.ncbi.nlm.nih.gov/pubmed/36069818, https://www.researchsquare.com/article/rs-1720472/v1, https://www.ncbi.nlm.nih.gov/pubmed/35982660, https://www.ncbi.nlm.nih.gov/pubmed/35698452, https://emergency.cdc.gov/han/2022/han00467.asp, http://www.bccdc.ca/Health-Professionals-Site/Documents/COVID-treatment/Crushing_Paxlovid.pdf, https://www.medrxiv.org/content/10.1101/2022.05.18.22275234v1, https://covid19-druginteractions.org/prescribing_resources, https://www.ontariohealth.ca/sites/ontariohealth/files/2022-04/PaxlovidClinicalGuide.pdf, https://www.ncbi.nlm.nih.gov/pubmed/35680135, https://www.ncbi.nlm.nih.gov/pubmed/21937987, https://www.ncbi.nlm.nih.gov/pubmed/32556272, https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/people-with-medical-conditions.html, https://www.ncbi.nlm.nih.gov/pubmed/24135775, The COVID-19 Treatment Guidelines Panel (the Panel) recommends using, For recommendations on using ritonavir-boosted nirmatrelvir in nonhospitalized children with COVID-19, see. But the study might not translate well to the U.S. because Qatar's population is much younger with only 9% of its residents age 50 or older, compared with more than a third of all Americans. See Guidance for use of Janssen COVID-19 VaccineandUse of the Janssen (Johnson & Johnson) COVID-19 Vaccine for information on GBS and Janssen COVID-19 Vaccine. Quarantine. Oral nirmatrelvir for high-risk, nonhospitalized adults with COVID-19. COVID-19 rapidly spreads from person-to-person contact and is also transmitted as it can stay alive and contagious for many days on surfaces. Should I wear a mask if I have a weak immune system? Is It Safe to Get a COVID-19 Booster While You Have COVID-19? - GoodRx Official websites use .govA .gov website belongs to an official government organization in the United States. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. %%EOF People who were initially immunized with . 2022. Antibody testing is not currently recommended to assess the need for vaccination in an unvaccinated person or to assess immunity to SARS-CoV-2 following COVID-19 vaccination or after SARS-CoV-2 infection. Can a monovalent mRNA vaccine (i.e., Moderna or Pfizer-BioNTech) be used for the booster dose? According to the CDC, after a COVID-19 infection, you can get a booster if: Your symptoms have resolved. For additional information on the vaccination schedule, see: Yes. Ages 6 months 4 years and completed Pfizer-BioNTech primary series: No booster dose is recommended at this time. 2023 CNBC LLC. No. If a patient requires hospitalization after starting treatment, the full 5-day treatment course of ritonavir-boosted nirmatrelvir should be completed unless there are drug-drug interactions that preclude its use. Should they be vaccinated against COVID-19? Dr. Ashish Jha, White House Covid response coordinator, said people who were recently infected can wait a few months before getting an omicron booster. Canada recommends waiting 3 months after COVID-19 infection - CBC Doses administered at any time after the recommended interval are valid. Rai DK, Yurgelonis I, McMonagle P, et al. After the dose has been repeated, continue with the recommended vaccination schedule (i.e., complete the primary series with a monovalent Moderna vaccine, then administer a bivalent booster dose at least 2 months after completion of the primary series). For more information, see vaccine administration errors and deviations. Phone the call centre if you need help booking an appointment. The dose should be reduced to nirmatrelvir 150 mg with ritonavir 100 mg twice daily in patients with moderate renal impairment (i.e., those with an estimated glomerular filtration rate [eGFR] of 30 to <60 mL/min). Jayk Bernal A, Gomes da Silva MM, Musungaie DB, et al. For more information, see COVID-19 Vaccines While Pregnant or Breastfeeding. Can they get a bivalent booster dose? Available at: (CTC) BCTC, COVID Therapy Review and Advisory Working Group (CTRAWG). Continue with the recommended vaccination schedule (i.e., complete the primary series with a monovalent Pfizer-BioNTech vaccine, then administer a bivalent booster dose at least 2 months after completion of the primary series). Antibody tests for SARS-CoV-2 look for the presence of antibodies made in response to a previous infection or vaccination. No. The EUA states that ritonavir-boosted nirmatrelvir is not recommended for patients with an eGFR of <30 mL/min until more data are available to establish appropriate dosing.3 Additional information is available in the initial FDA Center for Drug Evaluation and Research review for the EUA of ritonavir-boosted nirmatrelvir.15 Clinical experience on the use of ritonavir-boosted nirmatrelvir in patients who require hemodialysis is limited.24 Based on limited data, some groups have proposed dosing adjustments for ritonavir-boosted nirmatrelvir in patients with an eGFR of <30 mL/min and those who require hemodialysis.25-27 A clinical trial (ClinicalTrials.gov Identifier NCT05487040) that will evaluate the use of ritonavir-boosted nirmatrelvir in patients with COVID-19 and severe renal impairment is currently underway. When you get infected with the coronavirus, your immune system mounts a series of responses that bulk up the bodys defenses against future infections. Is there a maximum interval between doses 1 and 2 of a COVID-19 primary vaccination series? What do antibody tests tell us about immunity, and should these tests influence the decision to vaccinate or revaccinate? I was vaccinated in another country. Early experience with modified dose nirmatrelvir/ritonavir in dialysis patients with coronavirus disease-2019. If a person moves from a younger age group to an older age group during the primary series or between the primary series and receipt of the booster dose, they should receive the vaccine dosage for the older age group for all subsequent doses with the following exception: The Food and Drug Administration (FDA) authorization requires that children who receive the Pfizer-BioNTech COVID-19 Vaccine and transition from age 4 years to 5 years during the primary series must complete the series they start. Who can get a COVID-19 vaccine booster? A woman receives a booster shot at a pop-up vaccination clinic in Las Vegas on Dec. 21. In a prebirth-to-lactation study, an 8% decrease in body weight was observed on Postnatal Day 17 in the offspring of rats who received nirmatrelvir and had systemic exposures that were 8 times higher than the clinical exposures at the authorized human dose. 1928 0 obj <>/Filter/FlateDecode/ID[<3F544AE364F8124FBF39416F3C549081><9CEB8DA5CD9B424CA4573F7CD23B80B2>]/Index[1913 29]/Info 1912 0 R/Length 88/Prev 899777/Root 1914 0 R/Size 1942/Type/XRef/W[1 3 1]>>stream You've isolated for the recommended . The CDC cleared a fourth dose of the old vaccines in March for this age group. How Long After Having Covid-19 Should You Wait To Get The Booster Vaccine? U.S. health officials believe the new boosters will provide stronger and more durable protection against Covid because the shots target the omicron BA.5 variant, whereas the old vaccines were developed against the original strain of the virus that emerged in Wuhan, China, in 2019. Greasley SE, Noell S, Plotnikova O, et al. Local indiana news 3 hours ago The State of Emergency is over, but COVID-19 is still here. COVID-19 Vaccine Booster Questions & Answers - California A 2-dose course is recommended for optimal protection. Katzenmaier S, Markert C, Riedel KD, et al. People who recently caught Covid can wait to get omicron booster Ritonavir-Boosted Nirmatrelvir (Paxlovid) | COVID-19 Treatment Guidelines While nearly 22 million adults 50 and older have received a second booster dose, most people 5 and . Yes. For more information see: ATAGI guidance on myocarditis and pericarditis after mRNA COVID-19 vaccines. Forty-seven percent of the patients tested negative for SARS-CoV-2 antibodies, and 66% started study treatment within 3 days of symptom onset. There are theoretical concerns that using a single antiviral agent in these patients may produce antiviral-resistant viruses. What to Do If You Were Exposed to COVID-19 | CDC 1941 0 obj <>stream Ages 6 months 4 years and completed the Moderna primary series: 1 bivalent Moderna booster dose. Early remdesivir to prevent progression to severe COVID-19 in outpatients. Data from Moderna's clinical trial of omicron BA.1 shots showed that people with a previous infection who received the booster had the strongest immune response. Available at: Hiremath S, McGuinty M, Argyropoulos C, et al. Ganatra S, Dani SS, Ahmad J, et al. Less than 60% of all Utahns are considered fully vaccinated, meaning it's been two weeks or more since completing their initial series of shots. For booster dose recommendations for people vaccinated outside the United States, seepeople who received COVID-19 vaccine outside the United States. Owen DR, Allerton CMN, Anderson AS, et al. Lactation is not a contraindication for the use of ritonavir-boosted nirmatrelvir. Adults 18 and older who got Moderna can get boosted . It isn't clear how long these effects might last. Looking for U.S. government information and services. A child can get the bivalent booster dose regardless of whether the third primary series dose was a monovalent or bivalent Pfizer-BioNTech vaccine. The following resources provide information on identifying and managing drug-drug interactions. Therapeutic brief: crushing nirmatrelvir/ritonavir (Paxlovid). The booster provides real material help against preventing you from getting Omicron, Dr. Thomas said. CDC recommends COVID-19 vaccination for all people who are pregnant, breastfeeding, recently pregnant, trying to get pregnant now, or who might become pregnant in the future. You just dont want to overwhelm your system, Dr. Ellebedy said. Everyone who can get a vaccine, should get one, the CDC stressed. Which COVID-19 vaccines are recommended for people with a history of Bells palsy? What is the guidance for a use of the monovalent Novavax COVID-19 vaccine for a booster dose? There is no revaccination formonovalentmRNA booster dose(s) received before or during treatment. Among these patients, dysgeusia and diarrhea occurred more frequently in ritonavir-boosted nirmatrelvir recipients than in placebo recipients (6% vs. 0.3% and 3% vs. 2%, respectively). Day 0 is the day of your last exposure to someone with COVID-19. When Can You Get Your Booster Shot After Recovering From COVID-19? People who previously received orthopoxvirus vaccination (either JYNNEOS or ACAM2000), particularly adolescent or young adult males, might consider waiting 4 weeks before receiving a COVID-19 vaccine (i.e., Moderna, Novavax, or Pfizer-BioNTech) because of the observed risk for myocarditis and pericarditis after receipt of ACAM2000 orthopoxvirus vaccine and COVID-19 vaccines (i.e., Moderna, Novavax, or Pfizer-BioNTech) and the unknown risk for myocarditis and pericarditis after JYNNEOS administration. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Can a child who completes a Pfizer-BioNTech primary series at ages 6 months4 years get a booster dose when they turn age 5 years? Nirmatrelvir, an orally active MPRO inhibitor, is a potent inhibitor of SARS-CoV-2 variants of concern. COVID-19 isolation and quarantine period Are COVID-19 vaccine boosters or extra shots recommended? FDA authorization allows for dosing options for certain other age transitions when a child ages from a younger to older age group. How do I verify if a person is moderately or severely immunocompromised? CDC periodically issues guidance and information on topics related to COVID-19, including the COVID-19 vaccine, data, and other topics. The role of combination antiviral therapy or a longer treatment duration in treating patients who are severely immunocompromised is not yet known. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. For more information see: If the incorrect formulation is administered: For more information on transitioning between age groups, see. Data is a real-time snapshot *Data is delayed at least 15 minutes. If a bivalent Pfizer-BioNTech vaccine is administered in error for a primary series dose: Do not repeat the dose. This applies to primary series and booster doses of vaccine. An 8-week interval might be optimal for some people, especially males ages 1239 years because of the small risk of myocarditis and pericarditis associated with Moderna, Novavax, and Pfizer-BioNTech COVID-19 vaccines. No increased risk of GBShas been identified with receipt of mRNA COVID-19 vaccines. But more than half of fully vaccinated Americans who are eligible for booster shots have not yet received them. Booster doses for children ages 6 months4 years who completed the Pfizer-BioNTech primary series are not currently authorized. Available at: Centers for Disease Control and Prevention. Aligned with the U.S. Centers for Disease Control and Prevention (CDC) and the Federal Food and Drug Administration (FDA) to expand emergency use authorization (EUA) of Moderna and Pfizer-BioNTech bivalent vaccines for children 6 months and older. People who are vaccinated and recently caught Covid can wait three months to get their next shot, according to guidance from the CDC. However, providers may administer 1 bivalent booster dose as a repeat dose based on clinical judgment and patient preference. How Soon After COVID-19 Should You Get Your Booster? - Health The country is responding to a new virus known as Coronavirus Disease 19 or COVID-19. Additionally, ritonavir is an inhibitor, inducer, and substrate of various other drug-metabolizing enzymes and/or drug transporters. Rebound of SARS-CoV-2 infection after nirmatrelvir-ritonavir treatment. Children ages 6 months4 years who completed the Moderna primary series are recommended to receive 1 bivalent Moderna booster dose. New COVID-19 booster shots specially formulated to fight multiple omicron variants are available now for children and adults ages 12 and over. For more information, see COVID-19 vaccines. A fourth dose was about 56% effective at preventing hospitalization from omicron BA.5 four months after receiving the shot, according to CDC data. Doses administered up to 4 days before the minimum interval, known as the 4-day grace period, are considered valid. There are no data on combining ritonavir-boosted nirmatrelvir with other antiviral therapies to treat nonhospitalized patients with COVID-19. Frequently Asked Questions about COVID-19 Vaccination | CDC Healthcare professionals should see Ending Isolation and Precautions for People with COVID-19. Californians continue to have access to vaccines, testing, and treatment to fight COVID-19. Able to Mask Isolation Guidance; Yes Stay home and isolate for at least the first 5 days; you are probably most infectious during these 5 days For more information, see Interchangeability of COVID-19 vaccine products. 3 "Two doses of a COVID-19 vaccine are less effective in preventing infection with Omicron than earlier variants, and booster doses partially restore that protection," Moss said. The Food and Drug Administration (FDA) issued an Emergency Use Authorization (EUA) for ritonavir-boosted nirmatrelvir on December 22, 2021, for the treatment of COVID-19.3. Omicron BA.1 and BA.2 also are no longer circulating in the U.S. Currently, a child in this age group who received a mixed 3-dose primary series with any combination of Moderna and Pfizer-BioNTech vaccines is not authorized to receive any booster dose. Recommendations of the Advisory Committee on Immunization Practices (ACIP) and the Centers for Disease Control and Prevention (CDC) COVID-19 vaccine approval or Emergency Use Authorization (EUA) by the U.S. Food and Drug Administration (FDA) CDC's Emergency Use Instructions (EUI) for FDA-approved vaccines "Boosters are safe, and people over the age of 50 can now get an additional booster 4 months after their prior dose to increase their protection further," Walensky said. COVID-19-related hospitalizations or all-cause deaths occurred by Day 28 in 5 of 697 patients (0.72%) in the ritonavir-boosted nirmatrelvir arm and in 44 of 682 patients (6.5%) in the placebo arm. People who were fully vaccinated within three months of the exposure. People who previously received COVID-19 vaccination (i.e., Moderna, Novavax, or Pfizer-BioNTech) may be given orthopoxvirus vaccine (either JYNNEOS or ACAM2000) without a minimum interval between vaccinations. See Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Concomitant Medications for more information. The COVID-19 Treatment Guidelines Panel (the Panel) is committed to updating this document to ensure that health care providers, patients, and policy experts have the most recent information regarding the optimal management of COVID-19 (see the Panel Roster for a list of Panel members). Ali Ellebedy, an immunologist at the Washington University School of Medicine in St. Louis, said that it might make sense to wait until youve fully recovered or can get a negative P.C.R. If you already had COVID-19 within the past 90 days, see specific testing recommendations. People who have stayed asymptomatic since the current COVID-19 exposure. According to the CDC, your protection against COVID-19 may decrease over time due to the virus' mutations. Studies of infants who were exposed to ritonavir through breast milk suggest that the amount of ritonavir that transfers through breast milk is negligible and not considered clinically significant.32 The decision to feed breast milk while taking ritonavir-boosted nirmatrelvir should take into consideration the benefits of breastfeeding, the need for the medication, any underlying risks of infant exposure to the drug, and the potential adverse outcomes of COVID-19. Can COVID-19 vaccines be administered at the same time as an orthopoxvirus (monkeypox) vaccine? The third primary series dose can be either a monovalent Moderna vaccine or a bivalent Pfizer-BioNTech vaccine. Can people with prior or current SARS-CoV-2 infection receive a COVID-19 vaccine? But more than half of fully vaccinated Americans. Federal health officials continue to recommend that everyone get vaccinated and boosted, regardless of whether they've had Covid-19 in the past. For the Panels recommendations on preferred and alternative antiviral therapies for outpatients with COVID-19, see Therapeutic Management of Nonhospitalized Adults With COVID-19. COVID-19 and Surgical Procedures: A Guide for Patients | ACS The new guidelines suggest that 90 percent of Americans can now stop wearing masks, according to TODAY. Studies also suggest that the antibodies produced after vaccination tend to remain at protective levels for longer. When ritonavir is used for 5 days, its induction properties are less likely to be clinically relevant than when the drug is used chronically (e.g., in people who take HIV protease inhibitors).30. Anderson AS, Caubel P, Rusnak JM, Investigators E-HT. Which COVID-19 vaccines are recommended for people with a history of Guillain-Barre syndrome (GBS)? The CDC recently expanded booster recommendations to. The Centers for Disease Control and Prevention (CDC) is saying that before getting your Covid-19 vaccine or vaccine booster you should consider waiting for three months after you first. For assistance with patient counseling and education related to COVID-19 testing and vaccination, see: For more detailed information, see:Interim Guidelines for COVID-19 Antibody Testing. In general, CDC recommends that people receive the age-appropriate vaccine dosage based on their age on the day of vaccination. The risk-benefit assessment for using ritonavir-boosted nirmatrelvir in these patients may include factors such as medical comorbidities, body mass index, vaccination status, and the number and severity of the risk factors for severe disease. Severely immunocompromised patients can experience prolonged periods of SARS-CoV-2 replication, which may lead to rapid viral evolution. Deo R, Choudhary MC, Moser C, et al. If a child age 6 months4 years completed the 3-dose primary series with the monovalent Pfizer-BioNTech vaccine, can they also get a bivalent Pfizer-BioNTech vaccine dose? For booster vaccination, Moderna and Pfizer-BioNTech are recommended. Ritonavir-boosted nirmatrelvir is contraindicated in this setting, as the delayed offset of enzyme induction can reduce the concentrations of nirmatrelvir and ritonavir, which may render the treatment ineffective against SARS-CoV-2. Am I considered fully vaccinated if I was vaccinated in another country? Therefore, concerns about the recurrence of symptoms should not be a reason to avoid using ritonavir-boosted nirmatrelvir.19,21,22. In patients with suspected renal impairment, clinicians may consider checking the patients renal function to inform the dosing of ritonavir-boosted nirmatrelvir. He also said that it takes "three to four days" after getting the vaccine for your body to start creating antibodies and longer to develop full protection. People who received two doses and caught Covid had more than 50% protection against infection. What to do if you were exposed to COVID-19? - Coronavirus What is the difference in the booster dose recommendation for children ages 6 months4 years who completed the Moderna vs Pfizer-BioNTech primary series? Food and Drug Administration. Get this delivered to your inbox, and more info about our products and services. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Should they be revaccinated? Resulting in a lower-than-authorized dose: Repeat the dose immediately (no minimum interval) with the age-appropriate dose and formulation. COVID-19 booster vaccine advice | Australian Government Department of There are no data on the use of nirmatrelvir in lactating people, but the data from animal studies are reassuring. Prior infection: Offer vaccination regardless of history of prior symptomatic or asymptomatic SARS-CoV-2 infection, including to people with prolonged post-COVID-19 symptoms and people who experienced SARS-CoV-2 infection (symptomatic or asymptomatic) after vaccination. If a patient accidently received a monovalent mRNA vaccine for the booster dose, the dose generally does not need to be repeated. Can pregnant or breastfeeding people be vaccinated? Thus, ritonavir-boosted nirmatrelvir should not be given within 2 weeks of administering a strong CYP3A4 inducer (e.g., St. Johns wort, rifampin). Children ages 6 months4 years who received 1 monovalent Moderna and 1 monovalent Pfizer-BioNTech vaccine dose for the first two doses of the primary series (in any order: Moderna then Pfizer-BioNTech or Pfizer-BioNTech then Moderna) should follow a 3-dose primary series schedule. The EPIC-HR study was a multinational randomized trial that compared the use of ritonavir-boosted nirmatrelvir PO twice daily for 5 days to placebo in nonhospitalized patients aged 18 years with mild to moderate COVID-19 who were at high risk of clinical progression. Clinical trials are needed to determine whether combination therapy has a role in the treatment of COVID-19. CDC says get vaccinated even after COVID infection - Popular Science Ritonavir-boosted nirmatrelvir should be offered to pregnant and recently pregnant patients with COVID-19 who qualify for this therapy based on the results of a risk-benefit assessment. Novavax COVID-19 vaccine for booster vaccination and Janssen COVID-19 Vaccine for primary series and booster vaccination should only be used in limited situations. CDC Releases New Guidance for COVID Isolation and Quarantine If you choose to, get tested on Day 6. Evaluating the interaction risk of COVID-19 therapies. Millions of people who have recently developed Covid-19 may have some new questions about their immunity. This will also allow for a more refined and durable response, he said. How Long After Having Covid Can I Get a Booster Shot? - The New York Times The vaccine is derived from the original strain of the coronavirus, and that doesnt really exist anymore, Dr. Ellebedy said. CDC guidance says waiting three months after infection to get another Covid shot can result in a stronger immune response. A bivalent mRNA vaccine is recommended for the booster dose. Can the bivalent mRNA vaccines (i.e., Moderna and Pfizer-BioNTech) be used for the primary series? No, children ages 6 months4 years who have completed the 3-dose Pfizer-BioNTech primary series with monovalent vaccine cannot get a dose of bivalent Pfizer-BioNTech vaccine. Because of the potential for significant drug-drug interactions with concomitant medications, this regimen may not be the optimal choice for all patients. However, if the second dose is administered after this interval, there is no need to restart the series. CDC Signs Off on COVID Vaccine Booster for Immunocompromised The treatment course of ritonavir-boosted nirmatrelvir for COVID-19 is 5 days. For more information on the recommended vaccination, see COVID-19 vaccination schedule for people who are not moderately or severely immunocompromised. The CDC should recommend a 6-month interval between a previous booster or infection and the new updated vaccine for healthy adults for two primary reasons: updated immunologic studies and. Emergency Use Authorization (EUA) for Paxlovid (nirmatrelvir tablets co-packaged with ritonavir tablets): Center for Drug Evaluation and Research (CDER) review. Children age 5 years who completed the Pfizer-BioNTech primary series are recommended to receive 1 bivalent Pfizer-BioNTech booster dose; they cannot get a Moderna booster dose. For more information on booster doses see schedules for: For booster dose recommendations for people vaccinated outside the United States, see people who received COVID-19 vaccine outside the United States. What should be done if a bivalent mRNA vaccine is administered in error as a primary dose?